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High resolution dynamic mapping of histone-DNA interactions in a nucleosome

The nature of the nucleosomal barrier which regulates access to the underlying DNA during many cellular processes is not fully understood. Here we present a detailed map of histone-DNA interactions along the DNA sequence to near basepair accuracy by mechanically unzipping single molecules of DNA, ea...

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Detalles Bibliográficos
Autores principales: Hall, Michael A., Shundrovsky, Alla, Bai, Lu, Fulbright, Robert M., Lis, John T., Wang, Michelle D.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635915/
https://www.ncbi.nlm.nih.gov/pubmed/19136959
http://dx.doi.org/10.1038/nsmb.1526