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High resolution dynamic mapping of histone-DNA interactions in a nucleosome
The nature of the nucleosomal barrier which regulates access to the underlying DNA during many cellular processes is not fully understood. Here we present a detailed map of histone-DNA interactions along the DNA sequence to near basepair accuracy by mechanically unzipping single molecules of DNA, ea...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635915/ https://www.ncbi.nlm.nih.gov/pubmed/19136959 http://dx.doi.org/10.1038/nsmb.1526 |