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Combination of Two but Not Three Current Targeted Drugs Can Improve Therapy of Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a cancer of the hematopoietic system and has been treated with the drug Imatinib relatively successfully. Drug resistance, acquired by mutations, is an obstacle to success. Two additional drugs are now considered and could be combined with Imatinib to prevent resist...

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Detalles Bibliográficos
Autores principales: Komarova, Natalia L., Katouli, Allen A., Wodarz, Dominik
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635955/
https://www.ncbi.nlm.nih.gov/pubmed/19204794
http://dx.doi.org/10.1371/journal.pone.0004423