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Loss of yata, a Novel Gene Regulating the Subcellular Localization of APPL, Induces Deterioration of Neural Tissues and Lifespan Shortening

BACKGROUND: The subcellular localization of membrane and secreted proteins is finely and dynamically regulated through intracellular vesicular trafficking for permitting various biological processes. Drosophila Amyloid precursor protein like (APPL) and Hikaru genki (HIG) are examples of proteins tha...

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Detalles Bibliográficos
Autores principales: Sone, Masaki, Uchida, Atsuko, Komatsu, Ayumi, Suzuki, Emiko, Ibuki, Ikue, Asada, Megumi, Shiwaku, Hiroki, Tamura, Takuya, Hoshino, Mikio, Okazawa, Hitoshi, Nabeshima, Yo-ichi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635962/
https://www.ncbi.nlm.nih.gov/pubmed/19209226
http://dx.doi.org/10.1371/journal.pone.0004466