The Comprehensive Native Interactome of a Fully Functional Tagged Prion Protein

The enumeration of the interaction partners of the cellular prion protein, PrP(C), may help clarifying its elusive molecular function. Here we added a carboxy proximal myc epitope tag to PrP(C). When expressed in transgenic mice, PrP(myc) carried a GPI anchor, was targeted to lipid rafts, and was gl...

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Detalles Bibliográficos
Autores principales: Rutishauser, Dorothea, Mertz, Kirsten D., Moos, Rita, Brunner, Erich, Rülicke, Thomas, Calella, Anna Maria, Aguzzi, Adriano
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635968/
https://www.ncbi.nlm.nih.gov/pubmed/19209230
http://dx.doi.org/10.1371/journal.pone.0004446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635968/
https://www.ncbi.nlm.nih.gov/pubmed/19209230
http://dx.doi.org/10.1371/journal.pone.0004446

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