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The Comprehensive Native Interactome of a Fully Functional Tagged Prion Protein
The enumeration of the interaction partners of the cellular prion protein, PrP(C), may help clarifying its elusive molecular function. Here we added a carboxy proximal myc epitope tag to PrP(C). When expressed in transgenic mice, PrP(myc) carried a GPI anchor, was targeted to lipid rafts, and was gl...
Autores principales: | Rutishauser, Dorothea, Mertz, Kirsten D., Moos, Rita, Brunner, Erich, Rülicke, Thomas, Calella, Anna Maria, Aguzzi, Adriano |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635968/ https://www.ncbi.nlm.nih.gov/pubmed/19209230 http://dx.doi.org/10.1371/journal.pone.0004446 |
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