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The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif

BACKGROUND: Argonaute (Ago) proteins interact with small regulatory RNAs to mediate gene regulatory pathways. A recent report by Kiriakidou et al. [1] describes an MC sequence region identified in Ago2 that displays similarity to the cap-binding motif in translation initiation factor 4E (eIF4E). In...

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Detalles Bibliográficos
Autores principales: Kinch, Lisa N, Grishin, Nick V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636766/
https://www.ncbi.nlm.nih.gov/pubmed/19159466
http://dx.doi.org/10.1186/1745-6150-4-2