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SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines

BACKGROUND: SET-NUP214 fusion resulting from a recurrent cryptic deletion, del(9)(q34.11q34.13) has recently been described in T-cell acute lymphoblastic leukemia (T-ALL) and in one case of acute myeloid leukemia (AML). The fusion protein appears to promote elevated expression of HOXA cluster genes...

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Detalles Bibliográficos
Autores principales: Quentmeier, Hilmar, Schneider, Björn, Röhrs, Sonja, Romani, Julia, Zaborski, Margarete, MacLeod, Roderick AF, Drexler, Hans G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636835/
https://www.ncbi.nlm.nih.gov/pubmed/19166587
http://dx.doi.org/10.1186/1756-8722-2-3