Upregulation of Phagocyte-Derived Catecholamines Augments the Acute Inflammatory Response

Following our recent report that phagocytic cells (neutrophils, PMNs, and macrophages) are newly discovered sources of catecholamines, we now show that both epinephrine and norepinephrine directly activate NFκB in macrophages, causing enhanced release of proinflammatory cytokines (TNFα, IL-1β, IL-6)...

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Detalles Bibliográficos
Autores principales: Flierl, Michael A., Rittirsch, Daniel, Nadeau, Brian A., Sarma, J. Vidya, Day, Danielle E., Lentsch, Alex B., Huber-Lang, Markus S., Ward, Peter A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636885/
https://www.ncbi.nlm.nih.gov/pubmed/19212441
http://dx.doi.org/10.1371/journal.pone.0004414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636885/
https://www.ncbi.nlm.nih.gov/pubmed/19212441
http://dx.doi.org/10.1371/journal.pone.0004414

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