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The Glutathione Biosynthetic Pathway of Plasmodium Is Essential for Mosquito Transmission

Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species. Plasmodium spp. have thioredoxin and glutathione (GSH) systems that are thought to play a major role as...

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Detalles Bibliográficos
Autores principales: Vega-Rodríguez, Joel, Franke-Fayard, Blandine, Dinglasan, Rhoel R., Janse, Chris J., Pastrana-Mena, Rebecca, Waters, Andrew P., Coppens, Isabelle, Rodríguez-Orengo, José F., Jacobs-Lorena, Marcelo, Serrano, Adelfa E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636896/
https://www.ncbi.nlm.nih.gov/pubmed/19229315
http://dx.doi.org/10.1371/journal.ppat.1000302