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Variations within oxygen-regulated gene expression in humans
The effects of hypoxia on gene transcription are mainly mediated by a transcription factor complex termed hypoxia-inducible factor (HIF). Genetic manipulation of animals and studies of humans with rare hereditary disease have shown that modifying the HIF pathway affects systems-level physiological r...
Autores principales: | , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636937/ https://www.ncbi.nlm.nih.gov/pubmed/19008490 http://dx.doi.org/10.1152/japplphysiol.90578.2008 |