Cargando…

Variations within oxygen-regulated gene expression in humans

The effects of hypoxia on gene transcription are mainly mediated by a transcription factor complex termed hypoxia-inducible factor (HIF). Genetic manipulation of animals and studies of humans with rare hereditary disease have shown that modifying the HIF pathway affects systems-level physiological r...

Descripción completa

Detalles Bibliográficos
Autores principales: Brooks, Jerome T. S., Elvidge, Gareth P., Glenny, Louisa, Gleadle, Jonathan M., Liu, Chun, Ragoussis, Jiannis, Smith, Thomas G., Talbot, Nick P., Winchester, Laura, Maxwell, Patrick H., Robbins, Peter A.
Formato: Texto
Lenguaje:English
Publicado: American Physiological Society 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636937/
https://www.ncbi.nlm.nih.gov/pubmed/19008490
http://dx.doi.org/10.1152/japplphysiol.90578.2008