Analysis of a conserved RGE/RGD motif in HCV E2 in mediating entry

BACKGROUND: Hepatitis C virus (HCV) encodes two transmembrane glycoproteins E1 and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been shown to bind cellular receptors. It is clear that HCV uses a multi-receptor complex to gain entry into susceptible cells, however key el...

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Detalles Bibliográficos
Autores principales: Rothwangl, Katharina B, Rong, Lijun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637243/
https://www.ncbi.nlm.nih.gov/pubmed/19171049
http://dx.doi.org/10.1186/1743-422X-6-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637243/
https://www.ncbi.nlm.nih.gov/pubmed/19171049
http://dx.doi.org/10.1186/1743-422X-6-12

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