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Analysis of a conserved RGE/RGD motif in HCV E2 in mediating entry
BACKGROUND: Hepatitis C virus (HCV) encodes two transmembrane glycoproteins E1 and E2 which form a heterodimer. E1 is believed to mediate fusion while E2 has been shown to bind cellular receptors. It is clear that HCV uses a multi-receptor complex to gain entry into susceptible cells, however key el...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637243/ https://www.ncbi.nlm.nih.gov/pubmed/19171049 http://dx.doi.org/10.1186/1743-422X-6-12 |