Conserved Protective Mechanisms in Radiation and Genetically Attenuated uis3(-) and uis4(-) Plasmodium Sporozoites

Immunization with radiation attenuated Plasmodium sporozoites (RAS) elicits sterile protective immunity against sporozoite challenge in murine models and in humans. Similarly to RAS, the genetically attenuated sporozoites (GAPs) named uis3(-), uis4(-) and P36p(-) have arrested growth during the live...

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Detalles Bibliográficos
Autores principales: Kumar, Kota Arun, Baxter, Peter, Tarun, Alice S., Kappe, Stefan H. I., Nussenzweig, Victor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637429/
https://www.ncbi.nlm.nih.gov/pubmed/19214236
http://dx.doi.org/10.1371/journal.pone.0004480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637429/
https://www.ncbi.nlm.nih.gov/pubmed/19214236
http://dx.doi.org/10.1371/journal.pone.0004480

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