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Differential Ligand Binding to a Human Cytomegalovirus Chemokine Receptor Determines Cell Type–Specific Motility

While most chemokine receptors fail to cross the chemokine class boundary with respect to the ligands that they bind, the human cytomegalovirus (HCMV)-encoded chemokine receptor US28 binds multiple CC-chemokines and the CX(3)C-chemokine Fractalkine. US28 binding to CC-chemokines is both necessary an...

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Detalles Bibliográficos
Autores principales: Vomaske, Jennifer, Melnychuk, Ryan M., Smith, Patricia P., Powell, Joshua, Hall, Laurel, DeFilippis, Victor, Früh, Klaus, Smit, Martine, Schlaepfer, David D., Nelson, Jay A., Streblow, Daniel N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637432/
https://www.ncbi.nlm.nih.gov/pubmed/19229316
http://dx.doi.org/10.1371/journal.ppat.1000304