Tumorigenic Potential of Olfactory Bulb-Derived Human Adult Neural Stem Cells Associates with Activation of TERT and NOTCH1

BACKGROUND: Multipotent neural stem cells (NSCs) have been isolated from neurogenic regions of the adult brain. Reportedly, these cells can be expanded in vitro under prolonged mitogen stimulation without propensity to transform. However, the constitutive activation of the cellular machinery require...

Descripción completa

Detalles Bibliográficos
Autores principales: Casalbore, Patrizia, Budoni, Manuela, Ricci-Vitiani, Lucia, Cenciarelli, Carlo, Petrucci, Giovanna, Milazzo, Luisa, Montano, Nicola, Tabolacci, Elisabetta, Maira, Giulio, Larocca, Luigi M., Pallini, Roberto
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637538/
https://www.ncbi.nlm.nih.gov/pubmed/19209236
http://dx.doi.org/10.1371/journal.pone.0004434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637538/
https://www.ncbi.nlm.nih.gov/pubmed/19209236
http://dx.doi.org/10.1371/journal.pone.0004434

Ejemplares similares