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Is Paromomycin an Effective and Safe Treatment against Cutaneous Leishmaniasis? A Meta-Analysis of 14 Randomized Controlled Trials

BACKGROUND: High cost, poor compliance, and systemic toxicity have limited the use of pentavalent antimony compounds (SbV), the treatment of choice for cutaneous leishmaniasis (CL). Paromomycin (PR) has been developed as an alternative to SbV, but existing data are conflicting. METHODOLOGY/PRINCIPAL...

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Detalles Bibliográficos
Autores principales: Kim, Dae Hyun, Chung, Hye Jin, Bleys, Joachim, Ghohestani, Reza F.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637543/
https://www.ncbi.nlm.nih.gov/pubmed/19221595
http://dx.doi.org/10.1371/journal.pntd.0000381