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Evidence for Co-Evolution between Human MicroRNAs and Alu-Repeats

This paper connects Alu repeats, the most abundant repetitive elements in the human genome and microRNAs, small RNAs that alter gene expression at the post-transcriptional level. Base-pair complementarity could be demonstrated between the seed sequence of a subset of human microRNAs and Alu repeats...

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Detalles Bibliográficos
Autores principales: Lehnert, Stefan, Van Loo, Peter, Thilakarathne, Pushpike J., Marynen, Peter, Verbeke, Geert, Schuit, Frans C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637760/
https://www.ncbi.nlm.nih.gov/pubmed/19209240
http://dx.doi.org/10.1371/journal.pone.0004456