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Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4(+ )T cells

BACKGROUND: Infection with HIV-1 has been shown to alter expression of a large array of host cell genes. However, previous studies aimed at investigating the putative HIV-1-induced modulation of host gene expression have been mostly performed in established human cell lines. To better approximate na...

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Detalles Bibliográficos
Autores principales: Imbeault, Michaël, Ouellet, Michel, Tremblay, Michel J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637825/
https://www.ncbi.nlm.nih.gov/pubmed/19146679
http://dx.doi.org/10.1186/1742-4690-6-5