Improved homology-driven computational validation of protein-protein interactions motivated by the evolutionary gene duplication and divergence hypothesis

BACKGROUND: Protein-protein interaction (PPI) data sets generated by high-throughput experiments are contaminated by large numbers of erroneous PPIs. Therefore, computational methods for PPI validation are necessary to improve the quality of such data sets. Against the background of the theory that...

Descripción completa

Detalles Bibliográficos
Autores principales: Frech, Christian, Kommenda, Michael, Dorfer, Viktoria, Kern, Thomas, Hintner, Helmut, Bauer, Johann W, Önder, Kamil
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637843/
https://www.ncbi.nlm.nih.gov/pubmed/19152684
http://dx.doi.org/10.1186/1471-2105-10-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637843/
https://www.ncbi.nlm.nih.gov/pubmed/19152684
http://dx.doi.org/10.1186/1471-2105-10-21

Ejemplares similares