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Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data
BACKGROUND: ChIP-chip data are routinely used to identify transcription factor binding targets. However, the presence of false positives and false negatives in ChIP-chip data complicates and hinders analyses, especially when the binding targets for a specific transcription factor are compared across...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637844/ https://www.ncbi.nlm.nih.gov/pubmed/19152696 http://dx.doi.org/10.1186/1471-2105-10-23 |