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Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data

BACKGROUND: ChIP-chip data are routinely used to identify transcription factor binding targets. However, the presence of false positives and false negatives in ChIP-chip data complicates and hinders analyses, especially when the binding targets for a specific transcription factor are compared across...

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Detalles Bibliográficos
Autores principales: Datta, Debayan, Zhao, Hongyu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637844/
https://www.ncbi.nlm.nih.gov/pubmed/19152696
http://dx.doi.org/10.1186/1471-2105-10-23