Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli

BACKGROUND: In the vascular system, Notch receptors and ligands are expressed mainly on arteries, with Delta-like 4 (Dll4) being the only ligand known to be expressed early during the development of arterial endothelial cells and capillaries. Dll4 null embryos die very early in development with seve...

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Detalles Bibliográficos
Autores principales: Benedito, Rui, Trindade, Alexandre, Hirashima, Masanori, Henrique, Domingos, da Costa, Luis Lopes, Rossant, Janet, Gill, Parkash S, Duarte, António
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637862/
https://www.ncbi.nlm.nih.gov/pubmed/19087347
http://dx.doi.org/10.1186/1471-213X-8-117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637862/
https://www.ncbi.nlm.nih.gov/pubmed/19087347
http://dx.doi.org/10.1186/1471-213X-8-117

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