Intranasal delivery of transforming growth factor-beta1 in mice after stroke reduces infarct volume and increases neurogenesis in the subventricular zone

BACKGROUND: The effect of neurotrophic factors in enhancing stroke-induced neurogenesis in the adult subventricular zone (SVZ) is limited by their poor blood-brain barrier (BBB) permeability. Intranasal administration is a noninvasive and valid method for delivery of neuropeptides into the brain, to...

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Detalles Bibliográficos
Autores principales: Ma, Minmin, Ma, Yuping, Yi, Xueming, Guo, Ruibing, Zhu, Wusheng, Fan, Xinying, Xu, Gelin, Frey, William H, Liu, Xinfeng
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637876/
https://www.ncbi.nlm.nih.gov/pubmed/19077183
http://dx.doi.org/10.1186/1471-2202-9-117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637876/
https://www.ncbi.nlm.nih.gov/pubmed/19077183
http://dx.doi.org/10.1186/1471-2202-9-117

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