Pdx-1 or Pdx-1-VP16 protein transduction induces β-cell gene expression in liver-stem WB cells

BACKGROUND: Pancreatic duodenal homeobox-1 (Pdx-1) or Pdx-1-VP16 gene transfer has been shown to induce in vitro rat liver-stem WB cell conversion into pancreatic endocrine precursor cells. High glucose conditions were necessary for further differentiation into functional insulin-producing cells. Pd...

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Detalles Bibliográficos
Autores principales: Delisle, Juliette Cuvelier, Martignat, Lionel, Dubreil, Laurence, Saï, Pierre, Bach, Jean-Marie, Louzier, Vanessa, Bösch, Steffi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637887/
https://www.ncbi.nlm.nih.gov/pubmed/19134185
http://dx.doi.org/10.1186/1756-0500-2-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637887/
https://www.ncbi.nlm.nih.gov/pubmed/19134185
http://dx.doi.org/10.1186/1756-0500-2-3

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