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Pdx-1 or Pdx-1-VP16 protein transduction induces β-cell gene expression in liver-stem WB cells
BACKGROUND: Pancreatic duodenal homeobox-1 (Pdx-1) or Pdx-1-VP16 gene transfer has been shown to induce in vitro rat liver-stem WB cell conversion into pancreatic endocrine precursor cells. High glucose conditions were necessary for further differentiation into functional insulin-producing cells. Pd...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637887/ https://www.ncbi.nlm.nih.gov/pubmed/19134185 http://dx.doi.org/10.1186/1756-0500-2-3 |