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A Rapid Crosstalk of Human γδ T Cells and Monocytes Drives the Acute Inflammation in Bacterial Infections

Vγ9/Vδ2 T cells are a minor subset of T cells in human blood and differ from other T cells by their immediate responsiveness to microbes. We previously demonstrated that the primary target for Vγ9/Vδ2 T cells is (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMB-PP), an essential metabolite produc...

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Detalles Bibliográficos
Autores principales: Eberl, Matthias, Roberts, Gareth W., Meuter, Simone, Williams, John D., Topley, Nicholas, Moser, Bernhard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637987/
https://www.ncbi.nlm.nih.gov/pubmed/19229322
http://dx.doi.org/10.1371/journal.ppat.1000308