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C/EBPβ Promotes Transition from Proliferation to Hypertrophic Differentiation of Chondrocytes through Transactivation of p57(Kip2)

BACKGROUND: Although transition from proliferation to hypertrophic differentiation of chondrocytes is a crucial step for endochondral ossification in physiological skeletal growth and pathological disorders like osteoarthritis, the underlying mechanism remains an enigma. This study investigated the...

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Detalles Bibliográficos
Autores principales: Hirata, Makoto, Kugimiya, Fumitaka, Fukai, Atsushi, Ohba, Shinsuke, Kawamura, Naohiro, Ogasawara, Toru, Kawasaki, Yosuke, Saito, Taku, Yano, Fumiko, Ikeda, Toshiyuki, Nakamura, Kozo, Chung, Ung-il, Kawaguchi, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638010/
https://www.ncbi.nlm.nih.gov/pubmed/19229324
http://dx.doi.org/10.1371/journal.pone.0004543