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Extracting transcription factor binding sites from unaligned gene sequences with statistical models

BACKGROUND: Transcription factor binding sites (TFBSs) are crucial in the regulation of gene transcription. Recently, chromatin immunoprecipitation followed by cDNA microarray hybridization (ChIP-chip array) has been used to identify potential regulatory sequences, but the procedure can only map the...

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Detalles Bibliográficos
Autores principales: Lu, Chung-Chin, Yuan, Wei-Hao, Chen, Te-Ming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638147/
https://www.ncbi.nlm.nih.gov/pubmed/19091030
http://dx.doi.org/10.1186/1471-2105-9-S12-S7