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Molecular docking studies of dithionitrobenzoic acid and its related compounds to protein disulfide isomerase: computational screening of inhibitors to HIV-1 entry

BACKGROUND: Entry of HIV-1 into human lymphoid requires activities of viral envelope glycoproteins gp120 and gp41, and two host-cell proteins, the primary receptor CD4 and a chemokine co-receptor. In addition, a third cell-surface protein called protein disulfide isomerase (PDI) is found to play a m...

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Detalles Bibliográficos
Autores principales: Gowthaman, Uthaman, Jayakanthan, Mannu, Sundar, Durai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638154/
https://www.ncbi.nlm.nih.gov/pubmed/19091013
http://dx.doi.org/10.1186/1471-2105-9-S12-S14