Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies

BACKGROUND: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segments in the germline. Partitioning the functional antibody sequences to their sourcing germline gene segments is vital not o...

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Detalles Bibliográficos
Autores principales: Wang, Xiaojing, Wu, Di, Zheng, Siyuan, Sun, Jing, Tao, Lin, Li, Yixue, Cao, Zhiwei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638160/
https://www.ncbi.nlm.nih.gov/pubmed/19091020
http://dx.doi.org/10.1186/1471-2105-9-S12-S20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638160/
https://www.ncbi.nlm.nih.gov/pubmed/19091020
http://dx.doi.org/10.1186/1471-2105-9-S12-S20

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