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Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
BACKGROUND: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segments in the germline. Partitioning the functional antibody sequences to their sourcing germline gene segments is vital not o...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638160/ https://www.ncbi.nlm.nih.gov/pubmed/19091020 http://dx.doi.org/10.1186/1471-2105-9-S12-S20 |