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Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in disease activity and serum vascular endothelial growth factor by IL-6 receptor inhibition therapy

We investigated the clinical efficacy and safety of tocilizumab (a humanized anti-IL-6 receptor antibody) monotherapy in active rheumatoid arthritis (RA) patients with an inadequate response to low dose methotrexate (MTX). In a multicenter, double-blind, randomized, controlled trial, 125 patients we...

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Detalles Bibliográficos
Autores principales: Nishimoto, Norihiro, Miyasaka, Nobuyuki, Yamamoto, Kazuhiko, Kawai, Shinichi, Takeuchi, Tsutomu, Azuma, Junichi, Kishimoto, Tadamitsu
Formato: Texto
Lenguaje:English
Publicado: Springer Japan 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638601/
https://www.ncbi.nlm.nih.gov/pubmed/18979150
http://dx.doi.org/10.1007/s10165-008-0125-1