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Prediction of DNA-binding residues in proteins from amino acid sequences using a random forest model with a hybrid feature

Motivation: In this work, we aim to develop a computational approach for predicting DNA-binding sites in proteins from amino acid sequences. To avoid overfitting with this method, all available DNA-binding proteins from the Protein Data Bank (PDB) are used to construct the models. The random forest...

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Detalles Bibliográficos
Autores principales: Wu, Jiansheng, Liu, Hongde, Duan, Xueye, Ding, Yan, Wu, Hongtao, Bai, Yunfei, Sun, Xiao
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638931/
https://www.ncbi.nlm.nih.gov/pubmed/19008251
http://dx.doi.org/10.1093/bioinformatics/btn583