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Prediction of DNA-binding residues in proteins from amino acid sequences using a random forest model with a hybrid feature
Motivation: In this work, we aim to develop a computational approach for predicting DNA-binding sites in proteins from amino acid sequences. To avoid overfitting with this method, all available DNA-binding proteins from the Protein Data Bank (PDB) are used to construct the models. The random forest...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2638931/ https://www.ncbi.nlm.nih.gov/pubmed/19008251 http://dx.doi.org/10.1093/bioinformatics/btn583 |