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Precision and recall estimates for two-hybrid screens

Motivation: Yeast two-hybrid screens are an important method to map pairwise protein interactions. This method can generate spurious interactions (false discoveries), and true interactions can be missed (false negatives). Previously, we reported a capture–recapture estimator for bait-specific precis...

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Detalles Bibliográficos
Autores principales: Huang, Hailiang, Bader, Joel S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639075/
https://www.ncbi.nlm.nih.gov/pubmed/19091773
http://dx.doi.org/10.1093/bioinformatics/btn640