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Reconstruction of transcriptional dynamics from gene reporter data using differential equations

Motivation: Promoter-driven reporter genes, notably luciferase and green fluorescent protein, provide a tool for the generation of a vast array of time-course data sets from living cells and organisms. The aim of this study is to introduce a modeling framework based on stochastic differential equati...

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Detalles Bibliográficos
Autores principales: Finkenstädt, Bärbel, Heron, Elizabeth A., Komorowski, Michal, Edwards, Kieron, Tang, Sanyi, Harper, Claire V., Davis, Julian R. E., White, Michael R. H., Millar, Andrew J., Rand, David A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639297/
https://www.ncbi.nlm.nih.gov/pubmed/18974172
http://dx.doi.org/10.1093/bioinformatics/btn562