Adventitial transplantation of blood outgrowth endothelial cells in porcine haemodialysis grafts alleviates hypoxia and decreases neointimal proliferation through a matrix metalloproteinase-9-mediated pathway—a pilot study

Purpose. We hypothesized that adventitial transplantation of blood outgrowth endothelial cells (BOEC) to the vein-to-graft anastomosis of polytetrafluoroethylene grafts will reduce neointimal hyperplasia by reducing hypoxia inducible factor-1α (HIF-1α), by increasing angiogenesis in a porcine model...

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Detalles Bibliográficos
Autores principales: Hughes, Deborah, Fu, Alex A., Puggioni, Alessandra, Glockner, James F., Anwer, Bilal, McGuire, Antonio M., Mukhopadhyay, Debabrata, Misra, Sanjay
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Experimental Nephrology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639314/
https://www.ncbi.nlm.nih.gov/pubmed/18786975
http://dx.doi.org/10.1093/ndt/gfn433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639314/
https://www.ncbi.nlm.nih.gov/pubmed/18786975
http://dx.doi.org/10.1093/ndt/gfn433

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