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Adventitial transplantation of blood outgrowth endothelial cells in porcine haemodialysis grafts alleviates hypoxia and decreases neointimal proliferation through a matrix metalloproteinase-9-mediated pathway—a pilot study
Purpose. We hypothesized that adventitial transplantation of blood outgrowth endothelial cells (BOEC) to the vein-to-graft anastomosis of polytetrafluoroethylene grafts will reduce neointimal hyperplasia by reducing hypoxia inducible factor-1α (HIF-1α), by increasing angiogenesis in a porcine model...
Autores principales: | Hughes, Deborah, Fu, Alex A., Puggioni, Alessandra, Glockner, James F., Anwer, Bilal, McGuire, Antonio M., Mukhopadhyay, Debabrata, Misra, Sanjay |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639314/ https://www.ncbi.nlm.nih.gov/pubmed/18786975 http://dx.doi.org/10.1093/ndt/gfn433 |
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