Effect of calcium-sensing receptor activation in models of autosomal recessive or dominant polycystic kidney disease

Background. Antagonists of relevant Gs protein-coupled and agonists of relevant Gi protein-coupled receptors lower renal cAMP and inhibit growth of renal cysts in animal models of human ARPKD (PCK rat) and/or ADPKD (Pkd2(−/WS25) mouse). A calcium-sensing receptor (CaR) is expressed in various tubula...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofang, Harris, Peter C., Somlo, Stefan, Batlle, Daniel, Torres, Vicente E.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639335/
https://www.ncbi.nlm.nih.gov/pubmed/18826972
http://dx.doi.org/10.1093/ndt/gfn527

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639335/
https://www.ncbi.nlm.nih.gov/pubmed/18826972
http://dx.doi.org/10.1093/ndt/gfn527

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