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Using least median of squares for structural superposition of flexible proteins
BACKGROUND: The conventional superposition methods use an ordinary least squares (LS) fit for structural comparison of two different conformations of the same protein. The main problem of the LS fit that it is sensitive to outliers, i.e. large displacements of the original structures superimposed. R...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639377/ https://www.ncbi.nlm.nih.gov/pubmed/19159484 http://dx.doi.org/10.1186/1471-2105-10-29 |