Using least median of squares for structural superposition of flexible proteins

BACKGROUND: The conventional superposition methods use an ordinary least squares (LS) fit for structural comparison of two different conformations of the same protein. The main problem of the LS fit that it is sensitive to outliers, i.e. large displacements of the original structures superimposed. R...

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Detalles Bibliográficos
Autores principales: Liu, Yu-Shen, Fang, Yi, Ramani, Karthik
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639377/
https://www.ncbi.nlm.nih.gov/pubmed/19159484
http://dx.doi.org/10.1186/1471-2105-10-29