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Pathological rate matrices: from primates to pathogens

BACKGROUND: Continuous-time Markov models allow flexible, parametrically succinct descriptions of sequence divergence. Non-reversible forms of these models are more biologically realistic but are challenging to develop. The instantaneous rate matrices defined for these models are typically transform...

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Detalles Bibliográficos
Autores principales: Schranz, Harold W, Yap, Von Bing, Easteal, Simon, Knight, Rob, Huttley, Gavin A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639438/
https://www.ncbi.nlm.nih.gov/pubmed/19099591
http://dx.doi.org/10.1186/1471-2105-9-550