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Comparative analysis of HIV-1-based lentiviral vectors bearing lyssavirus glycoproteins for neuronal gene transfer

BACKGROUND: The delivery of therapeutic genes to the central nervous system (CNS) using viral vectors represents an appealing strategy for the treatment of nerve injury and disorders of the CNS. Important factors determining CNS targeting include tropism of the viral vectors and retrograde transport...

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Detalles Bibliográficos
Autores principales: Federici, Thais, Kutner, Robert, Zhang, Xian-Yang, Kuroda, Hitoshi, Tordo, Noël, Boulis, Nicholas M, Reiser, Jakob
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639530/
https://www.ncbi.nlm.nih.gov/pubmed/19144125
http://dx.doi.org/10.1186/1479-0556-7-1