Oxaliplatin neurotoxicity – no general ion channel surface-charge effect

BACKGROUND: Oxaliplatin is a platinum-based chemotherapeutic drug. Neurotoxicity is the dose-limiting side effect. Previous investigations have reported that acute neurotoxicity could be mediated via voltage-gated ion channels. A possible mechanism for some of the effects is a modification of surfac...

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Detalles Bibliográficos
Autores principales: Broomand, Amir, Jerremalm, Elin, Yachnin, Jeffrey, Ehrsson, Hans, Elinder, Fredrik
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639537/
https://www.ncbi.nlm.nih.gov/pubmed/19138416
http://dx.doi.org/10.1186/1477-5751-8-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639537/
https://www.ncbi.nlm.nih.gov/pubmed/19138416
http://dx.doi.org/10.1186/1477-5751-8-2

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