A glycosylated recombinant human granulocyte colony stimulating factor produced in a novel protein production system (AVI-014) in healthy subjects: a first-in human, single dose, controlled study

BACKGROUND: AVI-014 is an egg white-derived, recombinant, human granulocyte colony-stimulating factor (G-CSF). This healthy volunteer study is the first human investigation of AVI-014. METHODS: 24 male and female subjects received a single subcutaneous injection of AVI-014 at 4 or 8 mcg/kg. 16 contr...

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Detalles Bibliográficos
Autores principales: Varki, Roslyn, Pequignot, Ed, Leavitt, Mark C, Ferber, Andres, Kraft, Walter K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639539/
https://www.ncbi.nlm.nih.gov/pubmed/19175929
http://dx.doi.org/10.1186/1472-6904-9-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639539/
https://www.ncbi.nlm.nih.gov/pubmed/19175929
http://dx.doi.org/10.1186/1472-6904-9-2

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