Targeting cyclin B1 inhibits proliferation and sensitizes breast cancer cells to taxol

BACKGROUND: Cyclin B1, the regulatory subunit of cyclin-dependent kinase 1 (Cdk1), is essential for the transition from G2 phase to mitosis. Cyclin B1 is very often found to be overexpressed in primary breast and cervical cancer cells as well as in cancer cell lines. Its expression is correlated wit...

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Detalles Bibliográficos
Autores principales: Androic, Ilija, Krämer, Andrea, Yan, Ruilan, Rödel, Franz, Gätje, Regine, Kaufmann, Manfred, Strebhardt, Klaus, Yuan, Juping
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639606/
https://www.ncbi.nlm.nih.gov/pubmed/19113992
http://dx.doi.org/10.1186/1471-2407-8-391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639606/
https://www.ncbi.nlm.nih.gov/pubmed/19113992
http://dx.doi.org/10.1186/1471-2407-8-391

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