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Fatness-Associated FTO Gene Variant Increases Mortality Independent of Fatness – in Cohorts of Danish Men

BACKGROUND: The A-allele of the single nucleotide polymorphism (SNP), rs9939609, in the FTO gene is associated with increased fatness. We hypothesized that the SNP is associated with morbidity and mortality through the effect on fatness. METHODOLOGY/PRINCIPAL FINDINGS: In a population of 362,200 Dan...

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Detalles Bibliográficos
Autores principales: Zimmermann, Esther, Kring, Sofia I. I., Berentzen, Tina L., Holst, Claus, Pers, Tune H., Hansen, Torben, Pedersen, Oluf, Sørensen, Thorkild I. A., Jess, Tine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639637/
https://www.ncbi.nlm.nih.gov/pubmed/19214238
http://dx.doi.org/10.1371/journal.pone.0004428