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Identification of Three Classes of Heteroaromatic Compounds with Activity against Intracellular Trypanosoma cruzi by Chemical Library Screening

The development of new drugs against Chagas disease is a priority since the currently available medicines have toxic effects, partial efficacy and are targeted against the acute phase of disease. At present, there is no drug to treat the chronic stage. In this study, we have optimized a whole cell-b...

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Detalles Bibliográficos
Autores principales: Bettiol, Esther, Samanovic, Marie, Murkin, Andrew S., Raper, Jayne, Buckner, Frederick, Rodriguez, Ana
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639639/
https://www.ncbi.nlm.nih.gov/pubmed/19238193
http://dx.doi.org/10.1371/journal.pntd.0000384