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Ranking of binding and nonbinding peptides to MHC class I molecules using inverse folding approach: Implications for vaccine design

T cell recognition of the peptide–MHC complex initiates a cascade of immunological events necessary for immune responses. Accurate T-cell epitope prediction is an important part of the vaccine designing. Development of predictive algorithms based on sequence profile requires a very large number of e...

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Detalles Bibliográficos
Autores principales: Singh, Satarudra Prakash, Mishra, Bhartendu Nath
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639678/
https://www.ncbi.nlm.nih.gov/pubmed/19238199