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Probiotics Prevent Intestinal Barrier Dysfunction in Acute Pancreatitis in Rats via Induction of Ileal Mucosal Glutathione Biosynthesis

BACKGROUND: During acute pancreatitis (AP), oxidative stress contributes to intestinal barrier failure. We studied actions of multispecies probiotics on barrier dysfunction and oxidative stress in experimental AP. METHODOLOGY/PRINCIPAL FINDINGS: Fifty-three male Spraque-Dawley rats were randomly all...

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Detalles Bibliográficos
Autores principales: Lutgendorff, Femke, Nijmeijer, Rian M., Sandström, Per A., Trulsson, Lena M., Magnusson, Karl-Eric, Timmerman, Harro M., van Minnen, L. Paul, Rijkers, Ger T., Gooszen, Hein G., Akkermans, Louis M. A., Söderholm, Johan D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639703/
https://www.ncbi.nlm.nih.gov/pubmed/19223985
http://dx.doi.org/10.1371/journal.pone.0004512