Combined kinase inhibition modulates parkin inactivation

Mutations in the parkin gene cause autosomal-recessive, juvenile-onset parkinsonism, and parkin dysfunction may also play a role in the pathogenesis of sporadic Parkinson disease (PD). Although its precise function remains largely unknown, parkin seems to play a neuroprotective role. Several studies...

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Detalles Bibliográficos
Autores principales: Rubio de la Torre, Elena, Luzón-Toro, Berta, Forte-Lago, Irene, Minguez-Castellanos, Adolfo, Ferrer, Isidro, Hilfiker, Sabine
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640208/
https://www.ncbi.nlm.nih.gov/pubmed/19050041
http://dx.doi.org/10.1093/hmg/ddn407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640208/
https://www.ncbi.nlm.nih.gov/pubmed/19050041
http://dx.doi.org/10.1093/hmg/ddn407

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